Can we be forever young?

The progressive deterioration of the body’s physiological functions over the years, manifested by lack of energy, abnormal blood metabolic parameters and diseases, is called aging. For the last two centuries (19th and 20th), we have viewed aging as a natural and inevitable process. Recently, this paradigm has evolved and it has finally been recognized that the aging process can be slowed down and perhaps even reversed.

Many causes of aging have been identified, and new ones are still being discovered.

The metabolic cause of aging has been identified as the reduced activity of SIRT and PARP proteins, cellular anti-aging proteins. The main factor on which the activity of these proteins depends has been found to be the coenzyme NAD+ (1).

NAD+ is an essential molecule found in every cell in our bodies. NAD+ is a fuel and substrate that helps SIRTUINS regulate metabolism and PARP proteins repair DNA strands.

Until the age of 20, NAD+ levels are high. Unfortunately, with age, NAD+ levels in cells decline because its production mechanisms become less effective and its consumption increases (2, 3).

The consequence of a decrease in NAD+ levels is limited body regeneration and a deterioration in health and appearance.

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